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Saffron at high doses has been associated with GI upset in some people, though the doses used in these studies werent flagged for safety concerns
A meta-analysis of 12 randomized controlled trials on standard berberine found that supplementation leads to approximately 4.5 pounds of weight loss and a 1-centimeter reduction in waist circumference
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Anything below 95% should be rejected for serious research applications, as the cumulative effect of impurities over a multi-week protocol introduces unacceptable variability
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